A man intending to father a child should stop taking this medicine and check with his doctor right away. Using this medicine while you are pregnant can harm your unborn baby. If you can get pregnant, your doctor may do tests to make sure you are not pregnant before starting this medicine. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away. It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly.

2 Immune-Mediated Necrotizing Myopathy

The generic name, Atorvastatin, refers to the active ingredient, while Lipitor is the brand name. Both refer to the same statin medication used for managing cholesterol levels. Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking.

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. For more detailed atorvastatin dose information click the link below. Do not change your dose or stop taking any of your medications without your doctor’s advice. Take the liquid medicine on an empty stomach, at least 1 hour before a meal or 2 hours after a meal.

Atorvaliq In Children

Inform patients of the risk of myopathy and rhabdomyolysis when starting or increasing the LIPITOR dosage. In clinical trials, liver toxicity was reported in less than 1% (1 out of 100) of patients overall, but was more common with higher doses. Statins are extensively metabolized (broken down) by the liver.

  • It belongs to a class of cholesterol-lowering drugs called statins, which work by reducing the liver’s production of cholesterol.
  • Inform patients that LIPITOR may cause liver enzyme elevations and possibly liver failure.
  • Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
  • Don’t take this drug again if you’ve ever had an allergic reaction to it.

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Increases in HbA1c and fasting serum glucose levels have been reported with statins, including atorvastatin. The recommended atorvastatin oral route description and brand names starting dosage of Atorvaliq for pediatric patients aged 10 years of age and older with HeFH is 10 mg once daily; dosage range is 10 to 20 mg once daily. Atorvastatin (Lipitor) is a type of statin that lowers the level of cholesterol in the blood.

Cholesterol-lowering drugs

Atorvastatin may start to show its cholesterol-lowering effects within 2 weeks, but it may take up to 4 weeks for the full benefits to be seen. Regular monitoring of cholesterol levels by a healthcare professional is usually recommended. Please note that this is not an exhaustive list of side effects.

atorvastatin oral route description and brand names

The effect of 10 mg/day of atorvastatin on lipid levels was similar to that seen in previous clinical trials. While studies have not been conducted in patients with end-stage renal disease, hemodialysis is not expected to significantly enhance clearance of atorvastatin since the drug is extensively bound to plasma proteins. Plasma atorvastatin concentrations are lower (approximately 30% for Cmax and AUC) following evening drug administration compared with morning. Atorvastatin, as well as some of its metabolites, are pharmacologically active in humans. Individualization of drug dosage should be based on therapeutic response see DOSAGE AND ADMINISTRATION.

Warnings for people with certain health conditions

Keep all appointments for medical exams and tests while on this medicine. In particular, make sure that you discuss if you are using any of the following before using atorvastatin. Tell your healthcare provider if you have any of the following. People who are allergic to any of the following should not take atorvastatin. Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine if you have a major surgery, major injury, or you develop other serious health problems.

Pup development was delayed (rotorod performance at 100 mg/kg/day and acoustic startle at 225 mg/kg/day; pinnae detachment and eye-opening at 225 mg/kg/day). These doses correspond to 6 times (100 mg/kg) and 22 times (225 mg/kg) the human exposure at the MRHD, based on AUC. Patients who consume substantial quantities of alcohol and/or have a history of liver disease may be at increased risk for hepatic injury see Use In Specific Populations. Persistent elevations in serum transaminases, defined as more than 3 times the ULN and occurring on 2 or more occasions, occurred in 0.7% of patients who received LIPITOR in clinical trials. If you notice symptoms of liver disease, such as severe fatigue or weakness along with loss of appetite, stomach pain, dark-colored urine or yellowing of skin or eyes (jaundice), contact your doctor for medical advice immediately. No, Atorvastatin is not recommended for breastfeeding women.

  • While atorvastatin won’t cause you to be drowsy or sleepy right after you take it, some people do experience a level of lower energy and tiredness (fatigue) throughout the day.
  • Instruct patients or caregivers to use an oral dosing syringe or oral dosing cup to correctly measure the prescribed amount of medication.
  • Talk to your care team if you wish to become pregnant or think you might be pregnant.
  • In addition to this medicine, your doctor may change your diet to one that is low in fat, sugar, and cholesterol.
  • Do not take other medicines unless they have been discussed with your doctor.

atorvastatin – oral, Lipitor

Table 9 does not contain data comparing the effects of atorvastatin 10 mg and higher doses of lovastatin, pravastatin, and simvastatin. The drugs compared in the studies summarized in the table are not necessarily interchangeable. Persistent elevations in serum transaminases, defined as more than 3 times the ULN and occurring on 2 or more occasions, occurred in 0.7% of patients who received atorvastatin in clinical trials. The incidence of these abnormalities was 0.2%, 0.2%, 0.6%, and 2.3% for 10, 20, 40, and 80 mg, respectively. Tell your doctor if you are pregnant or plan to become pregnant before using Atorvaliq; it may harm a fetus.

Atorvastatin is not recommended for use during pregnancy as it may harm the unborn baby. It is important to discuss the potential risks and benefits with your healthcare provider if you are pregnant or planning to become pregnant. Common side effects of Atorvastatin may include muscle aches, joint pain, headache, stomach pain, nausea, and diarrhea. It is important to report any unusual or severe side effects to your healthcare provider. Managing metabolic syndrome often involves a combination of medications and lifestyle changes.